Lentiviral vector-based Japanese encephalitis immunogenic composition
US11779640B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Feb 19, 2020 |
| Grant date | Oct 10, 2023 |
| Priority date | — |
| Expiry date | Feb 19, 2040 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a lentiviral vector-based Japanese encephalitis (JE) immunogenic composition. The present invention is directed to a recombinant lentiviral vector expressing the precursor of membrane (prM) and the envelope (E) protein, in particular glycoprotein of a Japanese encephalitis virus (JEV) or immunogenic fragments thereof. The present invention also provides cells expressing the lentiviral vector, uses and methods to prevent a JEV infection in a mammalian host, especially in a human or an animal host, in particular a pig or a piglet, preferably a domestic pig or a domestic piglet.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.