Zika viral antigen constructs

US11780885B2 · kind B2 · utility

Assignees

• GLAXOSMITHKLINE BIOLOGICALS SA · BE
• The United States of America, as represented by the Secretary, Department of Health and Human Services · US

Inventors

• Kimberly Dowd · Columbia, US
• Barney Graham · Rockville, US
• Sung-Youl Ko · Rockville, US
• Wing-Pui Kong · Germantown, US
• John Mascola · Rockville, US
• Theodore Pierson · Poolesville, US
• Mayuri SHARMA · Cambridge, US
• Dong YU · Cambridge, US

Key dates

• Filing date: Nov 15, 2017
• Grant date: Oct 10, 2023
• Expiry date: May 23, 2038

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds useful as components of immunogenic compositions for the induction of an immunogenic response in a subject against viral infection, methods for their use in treatment, and processes for their manufacture are provided herein. The compounds comprise a nucleic acid construct comprising a sequence which encodes a Zika virus antigen.