Rapid elicitation of broadly neutralizing antibodies to HIV Env
US11795211B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 12, 2018 |
| Grant date | Oct 24, 2023 |
| Priority date | — |
| Expiry date | Aug 4, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16134
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab′)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.