Patent · US Active

Multi-specific antibodies with affinity for human A33 antigen and DOTA metal complex and uses thereof

US11858993B2 · kind B2 · utility

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24References
3Claims
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Key dates

Filing dateApr 13, 2021
Grant dateJan 2, 2024
Priority date
Expiry dateMar 25, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/33
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.