Compositions and methods for phosphoramidite and oligonucleotide synthesis
US11873316B2 · kind B2 · utility
4Cited by
42References
18Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 22, 2017 |
| Grant date | Jan 16, 2024 |
| Priority date | — |
| Expiry date | Jun 13, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure, among other things, provides technologies for oligonucleotide synthesis. In some embodiments, the present disclosure provides phosphoramidites and methods for synthesis thereof. In some embodiments, provided methods provides higher yields and/or purities. In some embodiments, provided methods remove byproducts without contact with an aqueous solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.