Inventor · Medford, MA, US

David Butler

43Patents
15h-index
73Co-inventors
80Inventor score

Filing activity: Sep 23, 2005 → May 12, 2023

Most-cited inventions

PatentTitleAreaCited byStatus
US9345780B2 Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components Chemistry; Metallurgy 237 Active
US8883202B2 Lipid compositions Emerging Cross-Sectional Technologies 95 Active
US8999351B2 Lipids and compositions for the delivery of therapeutics Emerging Cross-Sectional Technologies 91 Active
US9982257B2 Chiral control Chemistry; Metallurgy 63 Active
US9605019B2 Methods for the synthesis of functionalized nucleic acids Chemistry; Metallurgy 62 Active
US8575123B2 Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components Chemistry; Metallurgy 52 Active
US10450568B2 Oligonucleotide compositions and methods thereof Chemistry; Metallurgy 49 Active
US8722082B2 Lipids and compositions for the delivery of therapeutics Chemistry; Metallurgy 37 Active
US9682139B2 Lipids and compositions for the delivery of therapeutics Emerging Cross-Sectional Technologies 28 Active
US9220683B2 Lipids and compositions for the delivery of therapeutics Emerging Cross-Sectional Technologies 23 Active
US8962580B2 Chemical modifications of monomers and oligonucleotides with cycloaddition Emerging Cross-Sectional Technologies 22 Active
US10160969B2 Chiral design Chemistry; Metallurgy 21 Active
US10280192B2 Methods for the synthesis of functionalized nucleic acids Chemistry; Metallurgy 19 Active
US10590413B2 Chiral control Chemistry; Metallurgy 17 Active
US10815482B2 Chiral design Chemistry; Metallurgy 16 Active
US11013757B2 Oligonucleotides, compositions and methods thereof Chemistry; Metallurgy 14 Active
US9687550B2 Compositions for nucleic acid delivery Chemistry; Metallurgy 12 Active
US9999673B2 PEGylated lipids and their use for drug delivery Chemistry; Metallurgy 11 Active
US10117941B2 Lipids and compositions for the delivery of therapeutics Emerging Cross-Sectional Technologies 10 Active
US9764036B2 Lipids and compositions for the delivery of therapeutics Emerging Cross-Sectional Technologies 7 Active
US10456473B2 Lipid compositions Emerging Cross-Sectional Technologies 6 Active
US11603532B2 Oligonucleotide compositions and methods of use thereof Chemistry; Metallurgy 5 Active
US11407775B2 Compositions and methods for phosphoramidite and oligonucleotide synthesis Chemistry; Metallurgy 5 Active
US11597927B2 Oligonucleotide compositions and methods of use thereof Chemistry; Metallurgy 5 Active
US11718638B2 Compounds, compositions and methods for synthesis Chemistry; Metallurgy 4 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.