CD8+ t cell based immunosuppressive tumor microenvironment detection method
US11881286B2 · kind B2 · utility
0Cited by
0References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 25, 2020 |
| Grant date | Jan 23, 2024 |
| Priority date | — |
| Expiry date | Mar 10, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B25/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A machine-learning model (e.g., a clustering model) may be used to predict a phenotype of a tumor based on expression levels of a set of genes. The set of genes may have been identified using a same or different machine-learning model. The phenotype may include an immune-excluded, immune-desert or an inflamed/infiltrated phenotype. A treatment strategy and/or treatment recommendation may be identified based on the predicted phenotype.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.