Patent · US Active

IKAROS zinc finger family degraders and uses thereof

US11897862B2 · kind B2 · utility

1Cited by
5References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 7, 2023
Grant dateFeb 13, 2024
Priority date
Expiry dateApr 7, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/05
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure relates generally to compounds that bind to and act as degraders of an IKAROS Family Zinc Finger (IKZF) protein, such as IKZF2 (Helios) and/or IKZF4 (Eos). The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding and degradation of an IKZF protein, such as IKZF2 and/or IKZF4, including cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.