Substituted pyrimido[4,5-b][1,4]diazepines as PLK1 degradation inducers
US11939334B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Aug 10, 2022 |
| Grant date | Mar 26, 2024 |
| Priority date | — |
| Expiry date | Aug 10, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to a novel PLK1 degradation inducing compound having a structure according to Formula I, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.