Islet cell manufacturing compositions and methods of use

US11945795B2 · kind B2 · utility

Assignee

• Vertex Pharmaceuticals Incorporated · US

Inventors

• Austin Thiel · Southborough, US
• Jihad Yasin · Gardner, US
• Evrett Thompson · Woburn, US
• Felicia J. Pagliuca · Boston, US

Key dates

• Filing date: May 1, 2020
• Grant date: Apr 2, 2024
• Expiry date: Aug 23, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2506/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are compositions and methods useful for manufacturing SC-β cell, and isolated populations of SC-β cells for use in various applications, such as cell therapy.