Vertex Pharmaceuticals Incorporated
1,150Patents
816Active
1,150Granted
62Portfolio score
Filing activity: Jul 2, 1990 → Sep 4, 2024 · 316 expiring within 5 years
Most-cited patents
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5807876A | Inhibitors of IMPDH enzyme | Chemistry; Metallurgy | 191 | Expired |
| US6686193B2 | High throughput method and system for screening candidate compounds for activity against target ion channels | Physics | 186 | Expired |
| US7495103B2 | Modulators of ATP-binding cassette transporters | Physics | 154 | Active |
| US5585397A | Sulfonamide inhibitors of aspartyl protease | Chemistry; Metallurgy | 150 | Expired |
| US7553855B2 | Compositions of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide | Chemistry; Metallurgy | 142 | Active |
| US6825190B2 | Protein kinase inhibitors and uses thereof | Chemistry; Metallurgy | 135 | Expired |
| US7846951B2 | Thiazoles and oxazoles useful as modulators of ATP-binding cassette transporters | Chemistry; Metallurgy | 128 | Active |
| US7645789B2 | Indole derivatives as CFTR modulators | Physics | 127 | Active |
| US6054472A | Inhibitors of IMPDH enzyme | Chemistry; Metallurgy | 127 | Expired |
| US6784195B2 | Pyrazole compositions useful as inhibitors of ERK | Chemistry; Metallurgy | 126 | Expired |
| US7659268B2 | Modulators of ATP-binding cassette transporters | Chemistry; Metallurgy | 122 | Active |
| US7776905B2 | Modulators of ATP-binding cassette transporters | Physics | 119 | Active |
| US7691902B2 | Modulators of ATP-binding cassette transporters | Chemistry; Metallurgy | 115 | Active |
| US7754739B2 | Modulators of CFTR | Chemistry; Metallurgy | 115 | Active |
| US7598412B2 | Modulators of ATP-binding cassette transporters | Chemistry; Metallurgy | 115 | Expired |
| US7671221B2 | Modulators of ATP-Binding Cassette transporters | Human Necessities | 115 | Active |
| US5192773A | Immunosuppressive compounds | Chemistry; Metallurgy | 114 | Expired |
| US7741321B2 | Modulators of ATP-binding cassette transporters | Chemistry; Metallurgy | 114 | Active |
| US7553671B2 | Modular test tube rack | Emerging Cross-Sectional Technologies | 113 | Expired |
| US7407976B2 | Thiazoles and oxazoles useful as modulators of ATP-Binding Cassette transporters | Chemistry; Metallurgy | 113 | Expired |
| US6664247B2 | Pyrazole compounds useful as protein kinase inhibitors | Chemistry; Metallurgy | 109 | Expired |
| US7973169B2 | Modulators of ATP-Binding Cassette transporters | Physics | 107 | Active |
| US8642609B2 | Modulators of ATP-binding cassette transporters | Chemistry; Metallurgy | 107 | Active |
| US7956052B2 | Modulators of ATP-binding cassette transporters | Chemistry; Metallurgy | 106 | Active |
| US8163772B2 | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxypheny1]-1,4-dihydro-4-oxoquinoline-3-carboxamide | Chemistry; Metallurgy | 106 | Active |
Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.