Low noise amplifiers with feedback for nanopore applications
US11946894B2 · kind B2 · utility
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11References
19Claims
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Key dates
| Filing date | Feb 16, 2022 |
| Grant date | Apr 2, 2024 |
| Priority date | — |
| Expiry date | Nov 11, 2042 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH03F2200/294
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are devices, systems, and methods that can improve the SNR of nanopore measurements by mitigating the effect of parasitic capacitance between the sense electrode and the counter electrode. In some embodiments, a feedback circuit is used to inject a charge into the sense electrode to at least partially cancel the parasitic capacitance between the sense electrode and the counter electrode. In some embodiments, bootstrapping of a signal from the amplifier output or from the sense electrode is used to inject a charge on the counter electrode to substantially cancel the parasitic capacitance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.