Patent · US Active

N-methylated cyclic peptides and their prodrugs

US11965041B2 · kind B2 · utility

0Cited by

1References

12Claims

0Family size

Assignee

TECHNISCHE UNIVERSITÄT MÜNCHEN · DE

Inventors

Horst Kessler · Schwalbach, DE
Chaim Gilon · Jerusalem, IL
Amnon Hoffman · Jerusalem, IL
Michael Weinmuller · Simi Valley, US
Florian Rechenmacher · Munich, DE
Joseph FANOUS · Bat Yam, IL
Adi Klinger · Rishon LeZion, IL

Key dates

Filing date	Sep 17, 2018
Grant date	Apr 23, 2024
Priority date	—
Expiry date	Mar 15, 2040

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides N-methylated cyclic hexapeptides comprising RGD and at least one alanine residue. The present invention further provides prodrugs comprising the cyclic hexapeptides. Pharmaceutical compositions comprising said cyclic hexapeptides are also disclosed as well as methods of their production and use in treating integrin related conditions and diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.