Patent · US Active

Antibodies binding to HLA-A2/MAGE-A4

US11987632B2 · kind B2 · utility

0Cited by

34References

68Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Tina WEINZIERL · Schlieren, CH
Lydia Jasmin Hanisch · Schlieren, CH
Alexander BUJOTZEK · Penzberg, DE
Alejandro Carpy Gutierrez Cirlos · Munich, DE
Stefan Klostermann · Schwanau, DE
Christian Klein · Iffeldorf, DE
Simon Patrick KEISER · Aarau, CH
Tanja Fauti · Zürich, CH
Estelle Marrer-Berger · Basel, CH
Pablo Umana · Wollerau, CH

Key dates

Filing date	Dec 17, 2020
Grant date	May 21, 2024
Priority date	—
Expiry date	May 18, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.