Patent · US Active

Distance-based tissue state determination

US12031988B2 · kind B2 · utility

0Cited by

0References

21Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Fabien Gaire · Starnberg, DE
Karin Andersson · Stockholm, SE
Franziska BRAUN · Penzberg, DE
Konstanty Korski · Penzberg, DE
Fabian SCHMICH · Penzberg, DE

Key dates

Filing date	Oct 23, 2019
Grant date	Jul 9, 2024
Priority date	—
Expiry date	Apr 27, 2041

Classification

Technology area (CPC G)Physics
CPC primaryG06T2207/30024
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

An image analysis method for determining the biomedical state of a tissue sample. The method includes receiving a digital image of a tissue sample identifying the number and location of A-type cells and B-type cells, obtaining an observed relative distribution, obtaining a reference relative distribution of expected distances between reference A-type cells and reference B-type cells, computing a proximity score as a difference of the reference relative distribution and the observed relative distribution, computing a combined score comprising the proximity score and the density of the A-type cells and/or the density of the B-type cells, and using the combined score for determining the biomedical state of the tissue sample and/or outputting the combined score.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.