CAR-T reporter based diagnostic assays to detect tumor antigens in cancer patients
US12038441B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Oct 2, 2020 |
| Grant date | Jul 16, 2024 |
| Priority date | — |
| Expiry date | Nov 24, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/56972
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention generally relates to diagnostic assays using cell cultures, in particular to chimeric antigen receptor (CAR) expressing reporter cell assays to analyze samples, in particular patient samples, to diagnose cancer by quantifying the expression of tumor antigens and/or predicting clinical response to cancer immunotherapies. A further aspect of the present invention is to improve safety of e.g., cancer immunotherapies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.