RNA target enrichment or depletion of biological samples
US12071616B2 · kind B2 · utility
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Key dates
| Filing date | Mar 5, 2021 |
| Grant date | Aug 27, 2024 |
| Priority date | — |
| Expiry date | Feb 20, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6806
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of target enrichment or depletion from a sample with an analyte is described. A probe has one of a left-handed PNA pair and a targeting moiety, in which the left-handed PNA pair are a complementary pair of PNAs that are chiral and have a cyclic backbone modification that induces a left-handed helical structure. A capture surface has the other of the left-handed PNA pair; and the left-handed PNA pair bind to hybridize the probe to the capture surface, which may be a magnetic bead.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.