Antibodies selective for cells presenting EGFR at high density
US12084510B2 · kind B2 · utility
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Key dates
| Filing date | Feb 21, 2020 |
| Grant date | Sep 10, 2024 |
| Priority date | — |
| Expiry date | Aug 12, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/567
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Herein described are antibodies to epidermal growth factor receptor (EGER) having an EGER binding affinity that is sufficient to kill disease cells presenting EGFR at high density, but is insufficient for binding to normal cells. A therapeutic effect is thus achieved while avoiding adverse events that result from unintended binding to normal cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.