Oligonucleotides targeting RNA binding protein sites
US12084657B2 · kind B2 · utility
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Key dates
| Filing date | Jul 23, 2021 |
| Grant date | Sep 10, 2024 |
| Priority date | — |
| Expiry date | Nov 30, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/33
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to antisense oligonucleotides which are complementary to conserved TDP-43 binding sites on pre-mRNA transcripts, which are capable of restoring RNA binding protein function in the processing of multiple independent mRNAs in TDP-43 depleted cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.