Patent · US Active

Escherichia coli compositions and methods thereof

US12128095B2 · kind B2 · utility

0Cited by
28References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 15, 2022
Grant dateOct 29, 2024
Priority date
Expiry dateJul 14, 2042

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. Multivalent vaccines may be prepared by combining two or more monovalent immunogenic compositions for different E. coli serotypes. In one embodiment, the modified O-polysaccharide molecules are produced by a recombinant bacterium that includes a wzz gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.