Patent · US Active

Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains

US12139525B2 · kind B2 · utility

0Cited by
46References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 2, 2021
Grant dateNov 12, 2024
Priority date
Expiry dateAug 11, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/32
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to a novel targeted heterodimeric Fc fusion proteins comprising an IL-15/IL-15Rα Fc fusion protein and an antigen binding domain Fc fusion proteins. In some instances, the antigen binding domain binds to CD8, NKG2A, or NKG2D.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.