Delocalized lipophilic cation compounds and methods of use thereof
US12172976B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jan 10, 2020 |
| Grant date | Dec 24, 2024 |
| Priority date | — |
| Expiry date | Dec 9, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC09B23/105
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided are delocalized lipophilic cation (DLC) compounds and methods of using such compounds. Also provided are pharmaceutical compositions that include a DLC compound. Provided methods include methods of killing cells and methods of fluorescently labeling mitochondria by contacting the cells with a DLC compound of the present disclosure. Also provided are methods of imaging cell mitochondria, methods of determining whether a patient has a mitochondria related disease, and methods of treating a patient for a mitochondria related disease. Kits that include compounds of the present disclosure are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.