Patent · US Active

Differentiation of pancreatic endocrine cells

US12173324B2 · kind B2 · utility

0Cited by

15References

21Claims

0Family size

Assignee

Vertex Pharmaceuticals Incorporated · US

Inventors

George Harb · Boston, US
Chunhui Xie · Laishui, CN

Key dates

Filing date	Nov 16, 2022
Grant date	Dec 24, 2024
Priority date	—
Expiry date	Nov 16, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2501/415
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are compositions and methods related to differentiation of stem cells into pancreatic endocrine cells. In some aspects, the methods provided herein relate to generation of pancreatic β cell, α cell, δ cells, and EC cells in vitro. In some aspects, the disclosure provides pharmaceutical compositions including the cells generated according to the methods disclosed herein, as well as methods of treatment making use thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.