Patent · US Active

Minimal saponin analogues, synthesis and use thereof

US12187755B2 · kind B2 · utility

0Cited by

4References

13Claims

0Family size

Assignee

Memorial Sloan Kettering Cancer Center · US

Inventors

David Y. Gin · New York, US
Eric CHEA · Great Neck, US
Alberto Fernandez-Tejada · Kingston, US
Derek Shieh Tan · New York, US
Jason S. Lewis · New York, US
Jeffrey GARDNER · New York, US
NagaVaraKishore Pillarsetty · New York, US

Key dates

Filing date	Mar 14, 2022
Grant date	Jan 7, 2025
Priority date	—
Expiry date	Mar 14, 2042

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Truncated triterpene saponin analogues containing a trisaccharide or tetrasaccharide ester are disclosed. Also disclosed are pharmaceutical compositions comprising truncated saponin analogues and synthetic methods of producing the truncated saponin analogues. Another aspect of the present application relates to a method for immunizing a subject, comprising administering to the subject the pharmaceutical composition comprising a minimal saponin analogue and an antigen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.