Liquid chromatographic apparatus and air bubble removal method of liquid chromatographic apparatus
US12210003B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 5, 2021 |
| Grant date | Jan 28, 2025 |
| Priority date | — |
| Expiry date | Oct 20, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/328
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A liquid chromatographic apparatus which removes air bubbles during preparatory operation for apparatus startup includes a liquid feeding pump to feed a solvent, an injector to inject a sample into the solvent, a separation column to receive the solvent and the sample through the injector and separate the sample into components, a detector to detect the components supplied from the separation column, a pressure sensor to measure a pressure in a solvent flow channel of the liquid feeding pump, and a controller to control a purge operation for removing air bubbles in the solvent flow channel by the liquid feeding pump, determine whether a pressure change amount in the solvent flow channel measured by the pressure sensor during the purge operation is a specified change amount or larger, and complete the air bubble removal operation when the pressure change amount is the specified change amount or larger.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.