Stem cell derived islet differentiation
US12215355B2 · kind B2 · utility
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69References
20Claims
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Key dates
| Filing date | Feb 9, 2021 |
| Grant date | Feb 4, 2025 |
| Priority date | — |
| Expiry date | Jul 6, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/45
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods of producing β cells and precursors thereof utilizing a Wnt signaling inhibitor or PKC activator, or both. Also provided herein are in vitro cultures comprising said cells, methods of treating a subject with a disease characterized by high blood sugar levels over a prolonged period of time by administering said cells, and devices for encapsulating said cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.