Bispecific 2+1 contorsbodies

US12227594B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Maria Amann · Stintenberger Straße, CH
• Claudia Ferrara Koller · Schlieren, CH
• Reto Flury · Schlieren, CH
• Guy Georges · Habach, DE
• Sandra Grau-Richards · Schlieren, CH
• Alexander Haas · Munich, DE
• Friederike Hesse · Munich, DE
• Sabine Imhof-Jung · Planegg, DE
• Christian Klein · Iffeldorf, DE

Key dates

• Filing date: Oct 31, 2018
• Grant date: Feb 18, 2025
• Expiry date: Oct 31, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel bispecific antibodies consisting of two fusion polypeptides comprising two antigen binding domains capable of specific binding to a first target and one antigen binding domain capable of specific binding to a second target, and to methods of producing these molecules and to methods of using the same.