Hepatitis B vaccines and uses of the same

US12234261B2 · kind B2 · utility

Assignee

• Precigen, Inc. · US

Inventors

• Douglas E. Brough · Olney, US
• Cheryl G. Bolinger · Germantown, US
• Ramya Yarlagadda · Gaithersburg, US
• Vinodhbabu Kurella · Blacksburg, US
• Prabakaran Ponraj · Germantown, US
• Simon METENOU · Germantown, US
• Kuan-Fu Ding · Blacksburg, US

Key dates

• Filing date: Dec 2, 2022
• Grant date: Feb 25, 2025
• Expiry date: Dec 2, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2730/10134
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are engineered hepatitis B virus (HBV) molecular vaccine constructs. Vaccine constructs can also include ligand-inducible engineered gene switch systems for modulating expression of heterologous genes, such as a cytokines, in host cells.