Douglas E. Brough
61Patents
13h-index
37Co-inventors
84Inventor score
Filing activity: Sep 8, 1994 → Dec 2, 2022
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5994106A | Stocks of recombinant, replication-deficient adenovirus free of replication-competent adenovirus | Emerging Cross-Sectional Technologies | 180 | Expired |
| US5559099A | Penton base protein and methods of using same | Chemistry; Metallurgy | 130 | Expired |
| US5851806A | Complementary adenoviral systems and cell lines | Chemistry; Metallurgy | 122 | Expired |
| US6113913A | Recombinant adenovirus | Chemistry; Metallurgy | 93 | Expired |
| US5965541A | Vectors and methods for gene transfer to cells | Chemistry; Metallurgy | 75 | Expired |
| US5712136A | Adenoviral-mediated cell targeting commanded by the adenovirus penton base protein | Chemistry; Metallurgy | 58 | Expired |
| US5731190A | Penton base protein and methods of using same | Chemistry; Metallurgy | 48 | Expired |
| US6660521B2 | Use of trans-activation and CIS-activation to increase the persistence of a transgene in an at least E4-deficient adenovirus | Chemistry; Metallurgy | 41 | Expired |
| US6482616B1 | RCA-free adenoviral vector system and propagation method | Emerging Cross-Sectional Technologies | 33 | Expired |
| US7195896B2 | Complementary adenoviral vector systems and cell lines | Emerging Cross-Sectional Technologies | 28 | Expired |
| US6465253B1 | Vectors and methods for gene transfer to cells | Chemistry; Metallurgy | 22 | Expired |
| US6677156B2 | Non-adenoviral gene product-based complementing cells for adenoviral vectors | Chemistry; Metallurgy | 21 | Expired |
| US6682929B2 | Adenovector complementing cells | Chemistry; Metallurgy | 21 | Expired |
| US6821775B1 | Viral vector encoding pigment epithelium-derived factor | Chemistry; Metallurgy | 13 | Expired |
| US6951755B2 | Vectors and methods for gene transfer | Chemistry; Metallurgy | 12 | Expired |
| US6225113A | Use of trans-activation and cis-activation to modulate the persistence of expression of a transgene in an at least E4-deficient adenovirus | Chemistry; Metallurgy | 8 | Expired |
| US6649373B2 | Use of trans-activation and CIS-activation to modulate the persistence of expression of a transgene | Chemistry; Metallurgy | 8 | Expired |
| US6329200A | Plasmids for construction of eukaryotic viral vectors | Chemistry; Metallurgy | 7 | Expired |
| US9790519B2 | Modified serotype 28 adenoviral vectors | Chemistry; Metallurgy | 6 | Active |
| US8920813B2 | Adenoviral vector-based dengue fever vaccine | Emerging Cross-Sectional Technologies | 6 | Active |
| US10272162B2 | Affenadenovirus (gorilla) or adenoviral vectors and methods of use | Chemistry; Metallurgy | 6 | Active |
| US9617560B2 | Simian (gorilla) adenovirus or adenoviral vectors and methods of use | Chemistry; Metallurgy | 5 | Active |
| US6475757B2 | Plasmids for construction of eukaryotic viral vectors | Chemistry; Metallurgy | 5 | Expired |
| US8323663B2 | Adenoviral vector-based foot-and-mouth disease vaccine | Emerging Cross-Sectional Technologies | 4 | Active |
| US6440728B1 | Chimeric vectors comprising a phage packaging site and a portion derived from the genome of a eukaryotic virus | Chemistry; Metallurgy | 4 | Expired |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.