Patent · US Active

Substituted pyrazolo[1,5-a]pyrimidines as inhibitors of JAK kinases

US12247032B2 · kind B2 · utility

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Key dates

Filing dateDec 8, 2022
Grant dateMar 11, 2025
Priority date
Expiry dateDec 8, 2042

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P37/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined herein, and salts thereof, that are useful as JAK kinase inhibitors are described herein. Also provided are pharmaceutical compositions that include such a JAK inhibitor and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.