N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels
US12258333B2 · kind B2 · utility
0Cited by
43References
22Claims
0Family size
Assignee
Inventors
- Elizabeth Mary Beck
- Steven Durrant
- Sarah Elizabeth Skerratt
- Robert Pullin
- Gorka Etxebarria Jardi
- David Matthew Shaw
- Nadia Ahmad
- Christopher Wray
- Anisa Nizarali Virani
- Kiri North
- James Dodd
- Michael O'Donnell
- Bhairavi Galan
- Ronald Knegtel
- Ewa Iwona Chudyk
- Joanne Pinder
- Stephen Andrew Thomson
- Lidio Marx Carvalho Meireles
- Dean Stamos
- Yvonne Schmidt
- Joseph Pontillo
- Sara S. Hadida Ruah
- Timothy Neubert
- Dennis James Hurley
- Jinglan Zhou
Key dates
| Filing date | Oct 20, 2023 |
| Grant date | Mar 25, 2025 |
| Priority date | — |
| Expiry date | Oct 20, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.