Patent · US Active

Analytical system and method including switching between liquid chromatography fluidic streams

US12306147B2 · kind B2 · utility

0Cited by

4References

12Claims

0Family size

Assignees

Roche Diagnostics Operations, Inc. · US
HITACHI HIGH-TECH CORPORATION · JP

Inventors

Stefan Quint · Munich, DE
Tibor Toth · Marburg, DE
Aart Pieter Van Doorn · Munich, DE
Yuichiro Hashimoto · Tachikawa, JP

Key dates

Filing date	Oct 13, 2022
Grant date	May 20, 2025
Priority date	—
Expiry date	Jul 21, 2043

Classification

Technology area (CPC G)Physics
CPC primaryG01N2030/628
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present disclosure is related to an analytical system comprising a liquid chromatographic (LC) system comprising a plurality of fluidic streams alternately connectable to a common detector via a stream-selection valve connected to the detector via a valve-to-detector conduit. The analytical system further comprises a wash pump fluidically connected to the stream-selection valve and configured to connect to the valve-to-detector conduit between two consecutive fluidic streams in order to wash liquid from a previous fluidic stream out of the valve-to-detector conduit before liquid from a subsequent fluidic stream enters the valve-to-detector conduit. An analytical method comprising switching between the fluidic streams and washing in between is also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.