Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors
US12331022B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Apr 27, 2020 |
| Grant date | Jun 17, 2025 |
| Priority date | — |
| Expiry date | Aug 16, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to compounds of formula I that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.