Production of proteins in glutamine-free cell culture media
US12351641B2 · kind B2 · utility
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62References
30Claims
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Key dates
| Filing date | Nov 8, 2024 |
| Grant date | Jul 8, 2025 |
| Priority date | — |
| Expiry date | Nov 8, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2500/90
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates generally to glutamine-free cell culture media supplemented with arginine. The invention further concerns the production of recombinant proteins, such as therapeutic IgG antibodies, in a Chinese hamster ovary (CHO) host cell in a production phase culture medium that is essentially free of glutamine and comprises arginine in arginine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.