Optimization of yeast host cells for the production of heterologous proteins
US12365890B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Dec 19, 2023 |
| Grant date | Jul 22, 2025 |
| Priority date | — |
| Expiry date | Dec 19, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/81
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure concerns yeast host cell especially suited for the expression of heterologous proteins, such as heterologous enzymes. The yeast host cell of the present disclosure exhibits an alteration in the cAMP signaling pathway which allows achieving increased heterologous protein yield and associated biological activity. The yeast host cell can also exhibit polyploidy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.