CRISPR enzymes and systems with modified pam specificity
US12410416B2 · kind B2 · utility
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13References
23Claims
0Family size
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Key dates
| Filing date | Apr 19, 2017 |
| Grant date | Sep 9, 2025 |
| Priority date | — |
| Expiry date | Jul 8, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/80
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a novel DNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA. Aspects of the invention in particular relate to Cpf1 mutants having altered PAM specificity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.