Immunogenic compositions and use thereof

US12419948B2 · kind B2 · utility

Assignees

• The Broad Institute, Inc. · US
• President and Fellows of Harvard College · US
• The General Hospital Corporation · US
• TRUSTEES OF BOSTON UNIVERSITY · US

Inventors

• Pardis Sabeti · Cambridge, US
• Shira Weingarten-Gabbay · Cambridge, US
• Susan Klaeger · Cambridge, US
• Jenn Abelin · Cambridge, US
• Mohsan Saeed · Boston, US
• Nir Hacohen · Cambridge, US
• Siranush Sarkizova · Cambridge, US
• Steven A. Carr · Cambridge, US
• Karl Clauser · Cambridge, US

Key dates

• Filing date: Aug 31, 2021
• Grant date: Sep 23, 2025
• Expiry date: Feb 16, 2042

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/26
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Immunogenic compositions comprising one or more polypeptides, wherein the one or more polypeptides: is capable of binding to Major Histocompatibility Complex (MHC) class I, and is derived from one or more proteins of SARS-COV-2. Also provided include methods of treating and preventing diseases using the immunogenic compositions.