Glucose-responsive insulin conjugates
US12427187B2 · kind B2 · utility
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Key dates
| Filing date | Jun 1, 2020 |
| Grant date | Sep 30, 2025 |
| Priority date | — |
| Expiry date | Oct 2, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/62
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Glucose-responsive insulin conjugates that contain one or more linear oligomer sugar cluster are provided. Such insulin conjugates that may display a pharmacokinetic (PK) and/or pharmacodynamic (PD) profile that is responsive to the systemic concentrations of a saccharide such as glucose or alpha-methylmannose, even when administered to a subject in need thereof in the absence of an exogenous multivalent saccharide-binding molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.