Patent · US Expired

2,4-Diamino-5-benzylpyrimidines

US3931181A · kind A · utility

12Cited by
2References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 16, 1974
Grant dateJan 6, 1976
Priority date
Expiry dateJul 16, 1994

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08G63/6858
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

2,4-Diamino-5-benzylpyrimidines characterized by the formula ##SPC1## Wherein R.sup.1, R.sup.2, A.sup.1, Z and n are as hereinafter set forth, are described. The 2,4-diamino-5-benzylpyrimidines of the invention have useful antibacterial activity. More particularly, they block bacterial dihydrofolate reductase and potentiate the antibacterial activity of sulfonamides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.