Prostaglandin intermediates

US3991080A · kind A · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Hans Johann Mayer · Füllinsdorf, CH
• Albert E. Fischli · Riehen, CH
• Michael Klaus · Weil am Rhein, DE
• Alexander Wick · Montesson, FR

Key dates

• Filing date: Sep 10, 1975
• Grant date: Nov 9, 1976
• Expiry date: Sep 10, 1995

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C405/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Process for synthesizing a prostaglandin from a hexahydro-4-(lower alkoxy)-2H-oxireno[3,4]cyclopenta[1,2-b]furan, utilizing as an intermediate in the process a hexahydro-5-hydroxy-2-lower alkoxy-2H-cyclopentab]furan-4-carboxaldehyde, and the novel cyclopenta(b)furan intermediates of the process.