Benzylpyrimidines
US4039543A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 19, 1975 |
| Grant date | Aug 2, 1977 |
| Priority date | — |
| Expiry date | Dec 19, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/49
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Benzylpyrimidines of the formula ##STR1## wherein R.sup.1 and R.sup.2 each, independently, is amino, optionally C.sub.1.sub.-3 -alkyl-substituted pyrrolo, pyrrolidino, piperidino, -NHR.sup.3, -N(R.sup.3).sub.2, -NHR.sup.4, -N(R.sup.3)(R.sup.4),-NR.sup.3 COOR.sup.3, -NHCOOR.sup.3, -NHCONHR.sup.3, -NHCONH.sub.2 or -N(NO)R.sup.3 or wherein R.sup.3 is C.sub.1.sub.-4 -alkyl or C.sub.2.sub.-4 -alkenyl, R.sup.4 is acyl; Z is hydrogen, chlorine, bromine, pyrrolo, pyrrolidino, piperidino or morpholino or R.sup.3, OR.sup.3 or -N(R.sup.3).sub.2 ; A is an oxygen atom bonded to one of the cyclic nitrogen atoms; and n is 0 or 1 are prepared. The benzylpyrimidines are useful as potentiators of the activity of the sulfonamides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.