Immunostimulant agent, compositions thereof and methods for their preparation
US4076801A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | May 2, 1975 |
| Grant date | Feb 28, 1978 |
| Priority date | — |
| Expiry date | May 2, 1995 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55555
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The immunostimulant agent is extracted from splenic cells of animal origin from Ehrlich ascites cells or from bacteria, such as Bacillus subtilis or Saccharomyces cerevisiae. A suspension of these cells or of these bacteria is formed with a mixture of solvents containing a halogenated hydrocarbon and an alcohol. The insoluble fractions are separated, the liquid fraction evaporated under reduced pressure and at reduced temperature, and the solid residue taken up again in chloroform. The chloroform solution containing the abovementioned immunostimulant agent is recovered by filtration. A suspension in an injectable liquid vehicle of the immunostimulant agent is in the form of particles or micelles whose dimensions are sufficiently small for said suspension to be injectable in man or animal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.