Preparation of 2,4-diamino-5-(4-amino-3,5-substituted-benzyl)-pyrimidines
US4137411A · kind A · utility
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8Claims
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Key dates
| Filing date | Feb 1, 1978 |
| Grant date | Jan 30, 1979 |
| Priority date | — |
| Expiry date | Feb 1, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/49
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A benzylpyrimidines of the formula ##STR1## wherein r.sup.1 and R.sup.2 independently are C.sub.1-3 -alkyl or C.sub.1-3 -alkoxy, and R is hydrogen or lower alkyl, is treated with hydroxylamine or a salt thereof in polyphosphoric acid or alternatively, when R is hydrogen, is treated with sodium azide in polyphosphoric acid, to yield the corresponding 4-amino benzylpyrimidine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.