Propane-1,3-diol phosphatides and method of preparing the same

US4163748A · kind A · utility

Assignee

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Hansjorg Eibl · Bovenden, DE
• Alfar Nicksch · Höchberg, DE

Key dates

• Filing date: Oct 31, 1977
• Grant date: Aug 7, 1979
• Expiry date: Oct 31, 1997

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S516/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Propane-1,3-diol phosphatides of the formula ##STR1## are prepared from the corresponding 1-alkanoyl-propanediols by conversion o an intermediate alkanoyl-propanediol-phosphoric acid .beta.-bromoethyl ester with .beta.-bromoethylphosphoric acid dichloride, and amination of the intermediate. They are biodegradable surfactants useful in detergent compositions and as emulsifiers in foods. In the formula, n is an integer and 9 to 25, R.sub.1 and R.sub.2 may be hydrogen or alkyl having up to six carbon atoms, and R.sub.3, R.sub.4, R.sub.5 may be hydrogen or methyl, but at least one of R.sub.3, R.sub.4, and R.sub.5 is hydrogen when R.sub.1 and R.sub.2 are both hydrogen.