(S)-1-[2- (4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines
US4202978A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1978 |
| Grant date | May 13, 1980 |
| Priority date | — |
| Expiry date | Feb 8, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There are disclosed compounds of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of lower alkyl; R.sub.8 is selected from the group consisting of --O--(CH.sub.2).sub.n --wherein n is 2 to 20, ##STR2## and R.sub.6 is selected from the group consisting of hydrogen or lower alkoxy, and ##STR3## wherein R.sub.1 is selected from the group consisting of lower alkyl; R.sub.8 is selected from the group consisting of --O--(CH.sub.2).sub.n --wherein n is 2 to 20, ##STR4## and R.sub.6 is selected from the group consisting of hydrogen or lower alkoxy and racemates thereof. There are also disclosed processes and intermediates utilized to produce the end products. The end products have utility as agents exhibiting both .alpha. and selective .beta. adrenergic blocking action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.