Derivatives of amines and amino acids
US4267374A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 25, 1979 |
| Grant date | May 12, 1981 |
| Priority date | — |
| Expiry date | Jun 25, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C271/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel compounds of the formula ##STR1## wherein A is methylene, ethylene or ethylidene; R.sub.1 is --C.tbd.CH or --CH.dbd.CH.sub.2 ; R.sub.2 is hydrogen or COR wherein R is hydroxy, a straight or branched alkoxy group of from 1 to 8 carbon atoms, --NR.sub.4 R.sub.5 wherein each of R.sub.4 and R.sub.5 is hydrogen or a straight or branched lower alkyl group of from 1 to 4 carbon atoms or ##STR2## wherein R.sub.6 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; R.sub.a is hydrogen, ##STR3## alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy moiety has from 1 to 4 carbon atoms and is straight or branched or ##STR4## wherein R.sub.7 is selected from hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl and p-hydroxybenzyl; and R.sub.b has the same meaning as defined for R.sub.a except R.sub.b is not ##STR5## and R.sub.a and R.sub.b can be the same or different; with the provisos that when R.sub.2 is hydrogen, R.sub.1 is --C.tbd.H; when A is ethylidene, R.sub.2 is hydrogen; and when R.sub.a is ##STR6## A is methylene…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.