Inventor · Moraga, CA, US

Brian W. Metcalf

135Patents
24h-index
93Co-inventors
93Inventor score

Filing activity: Mar 18, 1975 → Jan 13, 2022

Most-cited inventions

PatentTitleAreaCited byStatus
US8410265B2 Processes for preparing JAK inhibitors and related intermediate compounds Emerging Cross-Sectional Technologies 112 Active
US9000161B2 Processes for preparing JAK inhibitors and related intermediate compounds Emerging Cross-Sectional Technologies 58 Active
US8940752B2 Pyrimidinones as PI3K inhibitors Chemistry; Metallurgy 58 Active
US9290506B2 Processes for preparing JAK inhibitors and related intermediate compounds Emerging Cross-Sectional Technologies 56 Active
US8993582B2 Processes for preparing JAK inhibitors and related intermediate compounds Emerging Cross-Sectional Technologies 56 Active
US9422279B2 Compounds and uses thereof for the modulation of hemoglobin Chemistry; Metallurgy 49 Active
US9018210B2 Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation Emerging Cross-Sectional Technologies 46 Active
US3960927A Olefinic derivatives of amino acids Human Necessities 45 Expired
US4317817A Novel steroid 5.alpha.-reductase inhibitors Chemistry; Metallurgy 45 Expired
US9012450B2 Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation Chemistry; Metallurgy 44 Active
US9458139B2 Compounds and uses thereof for the modulation of hemoglobin Chemistry; Metallurgy 44 Active
US9248199B2 1:1 adducts of sickle hemoglobin Human Necessities 42 Active
US4882319A Phosphonic acid substituted aromatic steroids as inhibitors of steroid 5-.alpha.-reductase Human Necessities 40 Expired
US4910226A Steroid 5-alpha-reductase inhibitors Chemistry; Metallurgy 40 Expired
US6489314B1 Epothilone derivatives and methods for making and using the same Chemistry; Metallurgy 35 Expired
US10034879B2 Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation Emerging Cross-Sectional Technologies 34 Active
US10017491B2 Compounds and uses thereof for the modulation of hemoglobin Chemistry; Metallurgy 33 Active
US7767675B2 Imidazotriazines and imidazopyrimidines as kinase inhibitors Chemistry; Metallurgy 33 Active
US5017568A Steriod 5-alpha-reductase inhibitors Chemistry; Metallurgy 31 Expired
US7304081B2 Amido compounds and their use as pharmaceuticals Chemistry; Metallurgy 31 Expired
US9434746B2 Pyrimidinones as PI3K inhibitors Chemistry; Metallurgy 28 Active
US4888336A Steroid 5-alpha-reductase inhibitors Chemistry; Metallurgy 28 Expired
US8461330B2 Imidazotriazines and imidazopyrimidines as kinase inhibitors Chemistry; Metallurgy 25 Active
US6589968B2 Epothilone compounds and methods for making and using the same Chemistry; Metallurgy 24 Expired
US8071624B2 N-substituted piperidines and their use as pharmaceuticals Chemistry; Metallurgy 24 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.