Method for producing tripdiolide, triptolide and celastrol
US4328309A · kind A · utility
12Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 2, 1980 |
| Grant date | May 4, 1982 |
| Priority date | — |
| Expiry date | Jul 2, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/91
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for the production of tripdiolide, triptolide and celastrol comprises the steps of: (a) preparing a cellular inoculum from Tripterygium wilfordii Hook F; (b) inoculating a nutrient growth medium with the cellular inoculum and incubating the inoculated growth medium at 20.degree.-30.degree. C. for up to 8 weeks to produce a cellular product; (c) harvesting the cellular product from the inoculated growth medium; and (d) isolating tripdiolide, triptolide and celastrol from the cellular product and supernatant inoculated growth medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.