Piperidinylalkyl quinazoline compounds, composition and method of use

US4335127A · kind A · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Jan Vandenberk · Beerse, BE
• Ludo Edmond Josephine Kennis · Lier, BE
• Marcel Jozef Maria Van der Aa · Kasterlee, BE
• Albert H. M. Th. Van Heertum · Vosselaar, BE

Key dates

• Filing date: Oct 12, 1979
• Grant date: Jun 15, 1982
• Expiry date: Oct 12, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/96
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel quinazoline derivatives, comprising in the heterocyclic part of their quinazoline nucleus at least one carbonyl or thiocarbonyl group and a particularly substituted piperidinyl-alkyl side chain, said compounds being potent serotonin-antagonists.