Process for purifying particles of biological origin, particularly the surface antigen of the virus of hepatitis B (AgHBs)
US4335214A · kind A · utility
4Cited by
6References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 5, 1980 |
| Grant date | Jun 15, 1982 |
| Priority date | — |
| Expiry date | Dec 5, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/83
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a process for purifying biological particles, particularly for purifying the surface antigen (HBs) of the hepatitis B virus. A suspension of this HBs antigen is subjected to rate zonal banding in a gradient inside a centrifuge equipped with a continuous-flow core. At the same time as the centrifugation operation is carried out, the suspension of particles to be purified is caused to circulate in a closed circuit in which the centrifuge is inserted. The band containing the purified biological particles is then collected in a way known per se.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.